| Product Name | Halofuginone (Synonyms: Tempostatin; RU-19110) | 
|---|---|
| CAS | 55837-20-2 | 
| Formula | C16H17BrClN3O3 | 
| MW | 414.68 | 
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity | |
|---|---|---|---|---|---|
| 
                                             There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.  | 
                                    |||||
| Product Name | Halofuginone (Synonyms: Tempostatin; RU-19110) | 
|---|---|
| CAS | 55837-20-2 | 
| Formula | C16H17BrClN3O3 | 
| MW | 414.68 | 
Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.