Alectinib Hydrochloride | CH5424802 Hydrochloride | RO5424802 Hydrochloride | AF-802 Hydrochloride | Alectinib HCl

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Price(USD)

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Product Overview

Product Name	Alectinib Hydrochloride (Synonyms: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride;Alectinib HCl)
CAS	1256589-74-8
Formula	C30H35ClN4O2
MW	519.08
MDL	MFCD27987893

Product details

Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

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