(E/Z)-Afatinib (Synonyms: (E/Z)-BIBW 2992; S)-阿法替尼)

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	(E/Z)-Afatinib (Synonyms: (E/Z)-BIBW 2992; （S)-阿法替尼)
CAS	439081-18-2
Formula	C24H25ClFN5O3
MW	485.94
Appearance	White to off-white powder
Storage condition	4°C, protect from light

Product details

(E/Z)-Afatinib ((E/Z)-BIBW 2992) is the mixture of (E)-Afatinib and (Z)-Afatinib. Afatinib (HY-10261) is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide (HY-17364), potently targeting to EGFRvIII-cMet signaling in glioblastoma cells.