Amphotericin B | NSC 527017 | LNS-AmB

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Product Overview

Product Name	Amphotericin B (Synonyms: NSC 527017;LNS-AmB)
CAS	1397-89-3
Formula	C47H73NO17
MW	924.09
Appearance	Yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.

Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration.
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