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Product Overview

Product Name	Paricalcitol
CAS	131918-61-1
Formula	C27H44O3
MW	416.64
MDL	MFCD08067734
Appearance	White to off-white powder
Storage condition	4°C, protect from light, stored under nitrogen

Product details

Paricalcitol, a selective VDR agonist, effectively suppresses PTH mRNA and inhibits parathyroid cell growth, treating secondary hyperparathyroidism in CKD. It's also associated with lower morbidity and improved survival rates compared to other VDRAs, with a favorable side-effect profile. Additionally, paricalcitol exhibits anti-inflammatory effects, potentially beneficial in managing CKD-related inflammation.

Related literature

In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/beta-catenin activation.

PMID: 22874762 DOI: 10.1152/ajprenal.00684.2011

The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload.

PMID: 22800987 DOI: 10.1016/j.jsbmb.2012.06.004

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History

CL2132

Paricalcitol

131918-61-1 99+%

Paricalcitol

Chemical safety data sheet(MSDS)