IWP-2 | 686770-61-6 | IWP2

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
10 mg	In-stock	$460.00	Visible after login	- +
20 mg	In-stock	$800.00	Visible after login	- +
50 mg	3-5days	$1360.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

10 mg

In-stock

$460.00

Visible after login

- +

20 mg

In-stock

$800.00

Visible after login

- +

50 mg

3-5days

$1360.00

Visible after login

- +

Product Overview

Product Name	IWP-2 (Synonyms: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2- d ]pyrimidin-2-yl)thio]-acetamide; IWP2)
CAS	686770-61-6
Formula	C22H18N4O2S3
MW	466.60
Appearance	White powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ.
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