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Niraparib (MK-4827)

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Catalog No：CL2258 CAS No.：1038915-60-4 MDLNo： Formula：C₁₉H₂₀N₄O MW：320.39

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Product Overview

Product Name	Niraparib (MK-4827)
CAS	1038915-60-4
Formula	C₁₉H₂₀N₄O
MW	320.39
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Niraparib, also known as MK4827, is an orally active, potent and selective poly(ADP-Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer.

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