Apatinib | Apatinib Free base | YN968D1| Rivoceranib | 阿帕替尼

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	$148.00	Visible after login	- +
5 mg	In-stock	$288.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

In-stock

$148.00

Visible after login

- +

5 mg

In-stock

$288.00

Visible after login

- +

Product Overview

Product Name	Apatinib \| Apatinib Free base \| YN968D1\| Rivoceranib
CAS	811803-05-1
Formula	C24H23N5O
MW	397.47
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.

Related literature

YN968D1 is a novel and selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase with potent activity in vitro and in vivo.

PMID: 21443688 PMCID: PMC11158267 DOI: 10.1111/j.1349-7006.2011.01939.x