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Selinexor | KPT-330

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Catalog No：CL2702 CAS No.：1393477-72-9 MDLNo： Formula：C17H11F6N7O MW：443.31

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$66.00	Visible after login	- +
10 mg	3-5days	$96.00	Visible after login	- +

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Product Overview

Product Name	Selinexor \| KPT-330
CAS	1393477-72-9
Formula	C17H11F6N7O
MW	443.31
Appearance	White to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor.

Related literature

KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia.

PMID: 23373539 PMCID: PMC3980736 DOI: 10.1111/bjh.12231

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CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.

PMID: 23588715 PMCID: PMC3883926 DOI: 10.1038/leu.2013.115

Read more

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