Tirofiban Hydrochloride monohydrate | Tirofiban HCl | L700462 hydrochloride monohydrate

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Tirofiban Hydrochloride monohydrate \| Tirofiban HCl \| L700462 hydrochloride monohydrate \| MK383 hydrochloride monohydrate
CAS	150915-40-5
Formula	C22H39ClN2O6S
MW	495.07
Appearance	White to off-white powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.

Related literature

Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.

PMID: 24751361 DOI: 10.1016/j.vph.2014.04.002

Effects of tirofiban on the reperfusion-related no-reflow in rats with acute myocardial infarction.

PMID: 23610574 PMCID: PMC3627702 DOI: 10.3969/j.issn.1671-5411.2013.01.009

The effect of tirofiban on microvascular thrombosis: crush model.