Tirofiban | L700462 | MK383

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Tirofiban \| L700462 \| MK383
CAS	144494-65-5
Formula	C22H36N2O5S
MW	440.60
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.

Related literature

Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.

PMID: 24751361 DOI: 10.1016/j.vph.2014.04.002

Effects of tirofiban on the reperfusion-related no-reflow in rats with acute myocardial infarction.

PMID: 23610574 PMCID: PMC3627702 DOI: 10.3969/j.issn.1671-5411.2013.01.009

The effect of tirofiban on microvascular thrombosis: crush model.

PMID: 15988269 DOI: 10.1097/01.prs.0000169938.26534.97