Crenolanib | CP-868596 | ARO 002 | 克莱拉尼

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
2 mg	3-5days	$48.00	Visible after login	- +
5 mg	3-5days	$80.00	Visible after login	- +
10mg	3-5days	$136.00	Visible after login	- +
25 mg	3-5days	$236.00	Visible after login	- +
50 mg	3-5days	$406.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

2 mg

3-5days

$48.00

Visible after login

- +

5 mg

3-5days

$80.00

Visible after login

- +

10mg

3-5days

$136.00

Visible after login

- +

25 mg

3-5days

$236.00

Visible after login

- +

50 mg

3-5days

$406.00

Visible after login

- +

Product Overview

Product Name	Crenolanib \| CP-868596 \| ARO 002
CAS	670220-88-9
Formula	C26H29N5O2
MW	443.54
Appearance	Off-white to light green powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Crenolanib is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases and with K_ds of 0.74 nM and 2.1 nM/3.2 nM, respectively.

Related literature

Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo.

PMID: 25328409 PMCID: PMC4196792 DOI: 10.2147/OTT.S68773

Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with STI571-resistant gastrointestinal stromal tumors.

PMID: 22745105 DOI: 10.1158/1078-0432.CCR-12-0625

The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations.

PMID: 25597754 PMCID: PMC7709138 DOI: 10.1007/s10637-015-0205-y

Sorry, no related items

History