Obicetrapib | TA-8995 | DEZ-001

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5 days	$196.00	Visible after login	- +
2 mg	3-5 days	$276.00	Visible after login	- +
5 mg	3-5 days	$428.00	Visible after login	- +
10 mg	3-5 days	$686.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5 days

$196.00

Visible after login

- +

2 mg

3-5 days

$276.00

Visible after login

- +

5 mg

3-5 days

$428.00

Visible after login

- +

10 mg

3-5 days

$686.00

Visible after login

- +

Product Overview

Product Name	Obicetrapib (Synonyms: TA-8995; DEZ-001)
CAS	866399-87-3
Formula	C32H31F9N4O5
MW	722.60
MDL	MFCD30533470
Appearance	White to light yellow powder
Storage condition	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

Product details

Obicetrapib, also known as AMG-899, TA-8995, and DEX-001, is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. TA-8995 dose dependently increased not only total and non-ABCA1-specific CEC but also ABCA1-specific CEC and preBeta-1 HDL particle levels.

Related literature

Tolerability, pharmacokinetics and pharmacodynamics of TA-8995, a selective cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.

PMID: 24628035 PMCID: PMC4243901 DOI: 10.1111/bcp.12380

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial.

PMID: 26047975 DOI: 10.1016/S0140-6736(15)60158-1

Cholesteryl ester transfer protein inhibitors: challenges and perspectives.

PMID: 27171534 DOI: 10.1080/14779072.2016.1189327

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