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Product Overview

Product Name	Anti-Human Her2xHer3 (Zenocutuzumab; MCLA-128; PB4188; R040517)
CAS	1969309-56-5
Storage condition	store at -20°C

Product details

Zenocutuzumab is a bispecific antibody targeting HER2 and HER3, effectively inhibiting NRG1-driven tumor growth. It employs a 'Dock & Block®' mechanism, preventing NRG1 binding to HER3 and subsequent oncogenic signaling.

Related literature

Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements.

PMID: 35135829 PMCID: PMC9394398 DOI: 10.1158/2159-8290.CD-21-1119

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History

Anti-Human ANGPTL3 Monoclonal Antibody(Evinacumab)

1446419-85-7 95+%

CLA1500

Anti-Human Her2xHer3 (Zenocutuzumab; MCLA-128; PB4188; R040517)

1969309-56-5 95+%

HL1480

Neohesperidin Dihydrochalcone(NHDC) (Synonyms: Neo-DHC; Neohesperidin DC; NHDC;Neohesperidin Dihydrochalcone;Neosperidin dihydrochalcone;Neohesperidosyl dihydrochalcone;NCI-c60764)

Sophoricoside | Genistein sophoricoside

Anti-Human Her2xHer3 (Zenocutuzumab; MCLA-128; PB4188; R040517)

Chemical safety data sheet(MSDS)