(S)-(+)-Camptothecin | CPT| (S)-(+)-Camptothecin | NSC-100880 |ADC Cytotoxin,Topoisomerase

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 g	In-stock	$600.00	Visible after login	- +
5 g	In-stock	$1000.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 g

In-stock

$600.00

Visible after login

- +

5 g

In-stock

$1000.00

Visible after login

- +

Product Overview

Product Name	(S)-(+)-Camptothecin \| CPT \| NSC-100880
CAS	7689-03-4
Formula	C20H16N2O4
MW	348.35
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Camptothecin is a cytotoxic, quinoline alkaloid, discovered as the active principle of extracts from the Chinese tree C. acuminate, that inhibits the DNA enzyme topoisomerase I (Top1). It binds the Top1-DNA cleavage complex, inducing DNA-strand breaks. Camptothecin has strong anti-tumor activity against a wide range of experimental tumors and inhibits both DNA and RNA synthesis in mammalian cells. It displays cytotoxity in HT-29 cells with an IC50 value of 10 nM and induces DNA damage at concentrations as low as 51 nM in whole cells and 12 nM in isolated nuclei in in vitro assays.

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History

HL1007

(S)-(+)-Camptothecin | CPT | NSC-100880

7689-03-4 98+%

HL1436

Geniposide (Synonyms: 栀子苷; 京尼平苷)

24512-63-8 98+%

(S)-(+)-Camptothecin | CPT | NSC-100880

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)