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Homoharringtonine (Synonyms: CGX-635; Omacetaxine mepesuccinate; HHT; Myelostat; NSC 141633)

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Catalog No:HL1109 CAS No.:26833-87-4 MDLNo:MFCD05618221 Formula:C29H39NO9 MW:545.62
Size Availability Price(USD) VIP Price (USD) Quantity
5 mg 3-5 days $58.00 Visible after login
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10 mg 3-5 days $96.00 Visible after login
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25 mg 3-5 days $156.00 Visible after login
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50 mg 3-5 days $256.00 Visible after login
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Chemical safety data sheet(MSDS)

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Product Overview
Product Name Homoharringtonine (Synonyms: CGX-635; Omacetaxine mepesuccinate; HHT; Myelostat; NSC 141633)
CAS26833-87-4
FormulaC29H39NO9
MW545.62
MDLMFCD05618221
AppearanceOff-white to yellow powder
Storage condition 4°C, protect from light
Product details

Homoharringtonine (Omacetaxine mepesuccinate; HHT) is a cytotoxic alkaloid derived from the Cephalotaxus tree, known for its significant antitumor properties. HHT acts primarily by inhibiting translation elongation, which disrupts protein synthesis crucial for cancer cell survival. This mechanism leads to the rapid degradation of several short-lived proteins, including Mcl-1 and c-Myc, triggering apoptosis in various cancer types, particularly in hematological malignancies such as acute myeloid leukemia (AML).
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