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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5 days	$58.00	Visible after login	- +
10 mg	3-5 days	$96.00	Visible after login	- +
25 mg	3-5 days	$156.00	Visible after login	- +
50 mg	3-5 days	$256.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5 days

$58.00

Visible after login

- +

10 mg

3-5 days

$96.00

Visible after login

- +

25 mg

3-5 days

$156.00

Visible after login

- +

50 mg

3-5 days

$256.00

Visible after login

- +

Product Overview

Product Name	Homoharringtonine (HHT) \| Omacetaxine mepesuccinate
CAS	26833-87-4
Formula	C29H39NO9
MW	545.62
MDL	MFCD05618221
Appearance	Off-white to yellow powder
Storage condition	4°C, protect from light

Product details

Homoharringtonine (Omacetaxine mepesuccinate; HHT) is a cytotoxic alkaloid derived from the Cephalotaxus tree, known for its significant antitumor properties. HHT acts primarily by inhibiting translation elongation, which disrupts protein synthesis crucial for cancer cell survival. This mechanism leads to the rapid degradation of several short-lived proteins, including Mcl-1 and c-Myc, triggering apoptosis in various cancer types, particularly in hematological malignancies such as acute myeloid leukemia (AML).

Related literature

Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells.

PMID: 26166037 PMCID: PMC4499885 DOI: 10.1038/srep08477

Homoharringtonine: an effective new natural product in cancer chemotherapy.

PMID: 8745664

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History

HL1109

Homoharringtonine (HHT) | Omacetaxine mepesuccinate

26833-87-4 98+%