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Temoporfin (Synonyms: m-THPC; KW2345;KW-2345)

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Catalog No：CL1040 CAS No.：122341-38-2 MDLNo： Formula：C44H32N4O4 MW：680.75

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	$126.00	Visible after login	- +
5 mg	In-stock	$415.00	Visible after login	- +

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Product Overview

Product Name	Temoporfin (Synonyms: m-THPC; KW2345;KW-2345)
CAS	122341-38-2
Formula	C44H32N4O4
MW	680.75
Appearance	Black purple powder
Storage condition	-20°C, protect from light, stored under nitrogen

Product details

Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells , When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor. Different approaches to using photodynamic therapy with temoporfin in palliative care are currently of interest.
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Related literature

Temoporfin (Foscan®, 5,10,15,20-tetra(m-hydroxyphenyl)chlorin)--a second-generation photosensitizer.

PMID: 21848905 DOI: 10.1111/j.1751-1097.2011.00986.x

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Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): comparison of treatment efficacy and distribution characteristics in vivo.

PMID: 24143087 PMCID: PMC3797282 DOI: 10.2147/IJN.S51002

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Effective treatment of liver metastases with photodynamic therapy, using the second-generation photosensitizer meta-tetra(hydroxyphenyl)chlorin (mTHPC), in a rat model.

PMID: 10574244 PMCID: PMC2362893 DOI: 10.1038/sj.bjc.6690736

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