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Bosutinib(SKI-606)

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Catalog No：CL2107 CAS No.：380843-75-4 MDLNo： Formula：C26H29Cl2N5O3 MW：530.45

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Product Overview

Product Name	Bosutinib(SKI-606)
CAS	380843-75-4
Formula	C26H29Cl2N5O3
MW	530.45
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy

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CL2107

Bosutinib(SKI-606)

380843-75-4 98+%