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Product Overview

Product Name	Maxacalcitol (Synonyms: 22-Oxacalcitriol)
CAS	103909-75-7
Formula	C26H42O4
MW	418.61
MDL	MFCD00871502
Appearance	White to off-white powder
Storage condition	4°C, protect from light, stored under nitrogen

Product details

Maxacalcitol, a vitamin D3 analog, acts as a potent orally active VDR agonist with minimal calcemic effects. It inhibits PTH mRNA expression and bone resorption, making it a promising candidate for hyperparathyroidism research. Additionally, Maxacalcitol exhibits anti-tumor activity by suppressing cell proliferation, migration, and inducing apoptosis through GPx-1 inhibition. Its unique properties suggest potential utility in treating psoriasis and underscore its significance in bone health and cancer research.

Related literature

Vitamin D3 analog maxacalcitol (OCT) induces hCAP-18/LL-37 production in human oral epithelial cells.

PMID: 27356607 DOI: 10.2220/biomedres.37.199

Effects of maxacalcitol ointment on skin lesions in patients with psoriasis receiving treatment with adalimumab.

PMID: 27450634 DOI: 10.1111/1346-8138.13515

The Influence of Maxacalcitol, Vitamin D3 Analog, on Detrusor Overactivity in Conscious Rats.

PMID: 27018369 DOI: 10.1016/j.urology.2016.03.008

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History

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Maxacalcitol (Synonyms: 22-Oxacalcitriol)

Chemical safety data sheet(MSDS)