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Product Overview

Product Name	Eldecalcitol (Synonyms: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3)
CAS	104121-92-8
Formula	C30H50O5
MW	490.72
MDL	MFCD25977156
Appearance	White to off-white powder
Storage condition	4°C, protect from light, stored under nitrogen

Product details

Eldecalcitol (ED-71), an oral vitamin D3 analog, is renowned for its potent inhibition of bone resorption and significant increase in bone mineral density, making it a valuable asset in osteoporosis treatment. Additionally, it exhibits anti-tumor properties by inhibiting cell proliferation, migration, and inducing apoptosis through the suppression of GPx-1, positioning it as a potential agent in cancer research and therapy.

Related literature

Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway.

PMID: 33223823 PMCID: PMC7671541 DOI: 10.2147/DDDT.S269223

Eldecalcitol inhibits the progression of oral cancer by suppressing the expression of GPx-1.

Oral Dis. 2021 Aug 24.

Eldecalcitol and calcitriol stimulates 'bone minimodeling,' focal bone formation without prior bone resorption, in rat trabecular bone.

PMID: 34431176 DOI: 10.1111/odi.14010

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