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Linifanib(ABT-869; AL-39324; RG3635)

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Catalog No:CL2480 CAS No.:796967-16-3 MDLNo:MFCD11840918 Formula:C21H18FN5O MW:375.40
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5 mg 3-5days $66.00 Visible after login
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10 mg 3-5days $96.00 Visible after login
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25 mg 3-5days $166.00 Visible after login
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Product Overview
Product Name Linifanib(ABT-869; AL-39324; RG3635)
CAS796967-16-3
FormulaC21H18FN5O
MW375.40
MDLMFCD11840918
AppearanceWhite to gray powder
Product details

Linifanib (formerly RG3635, ABT869, AL39324) is an orally bioavailable and ATP-competitive inhibitor of multiple kinases (e.g. VEGFR/PDGFR) with potential antitumor activity. Its IC50 values are 4 nM, 3 nM, 3 nM/4 nM, and 66 nM for KDR, CSF-1R, Flt-1/3, and PDGFRβ, respectively. Linifanib has strong antitumor efficaciousness in vivo and outstanding anti-proliferative activity in vitro.

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