A68930 hydrochloride; CAS: 130465-39-3

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Availability

Price(USD)

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Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	A68930 hydrochloride
CAS	130465-39-3
Formula	C16H18ClNO3
MW	307.77
MDL	MFCD00890904
Appearance	White to yellow powder
Storage condition	4°C, sealed storage, away from moisture

Product details

A-68930 hydrochloride, a selective dopamine D1 receptor agonist, exhibits potential in the research of bronchiectasis and Alzheimer's disease. It has been shown to ameliorate Aβ1-42-induced cognitive impairment and neuroinflammation in mice, suggesting its therapeutic potential for Alzheimer's disease treatment

Related literature

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium.

PMID: 29606146 PMCID: PMC5879645 DOI: 10.1186/s12931-018-0757-4

Advancements in Pharmacological Treatment of Alzheimer’s Disease: The Advent of Disease-Modifying Therapies (DMTs).

https://doi.org/10.3390/brainsci14100990

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History

CL3129

A68930 hydrochloride

130465-39-3 98+%