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Home > Category > Signaling Pathways > Apoptosis > RIP kinase > GSK583

GSK583

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Catalog No：CL2013 CAS No.：1346547-00-9 MDLNo： Formula：C20H19FN4O2S MW：398.45
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Product Overview
Product Name GSK583
CAS1346547-00-9
FormulaC20H19FN4O2S
MW398.45
AppearanceLight yellow to yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

GSK583 is a highly potent and selective inhibitor of RIP2 kinase with IC50 of 5 nM. GSK583 also inhibits both TNF-α and IL-6 production with IC50 of ~200 nM in explant cultures.

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