(3S,4S)-Tivantinib | 3S,4S)-ARQ 197 | ARQ 198

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	(3S,4S)-Tivantinib \| 3S,4S)-ARQ 197 \| ARQ 198
CAS	905854-03-7
Formula	C23H19N3O2
MW	369.42
Appearance	Off-white to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

(3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC).

Related literature

GSK3 alpha and beta are new functionally relevant targets of tivantinib in lung cancer cells.

PMID: 24215125 PMCID: PMC3944088 DOI: 10.1021/cb400660a